Information About Cancer

Breast cancer occurs due to mutations within the DNA of normal breast cells that encourage abnormal cell reproduction or limit ability of the cell to control the growth, this results in formation of tumors. The exact trigger that begins the process totally depends upon the causes of breast cancer in an individual, besides there are several other risk factors. Therefore, one should try to collect information about the disease that he or she is affected with. One can collect information on breast cancer through heath centers, reading books regarding health related topics or avail of disease related information from an expert. Taking proper care of oneself at home can be of help along with ongoing treatments.

Signs of breast cancer can include a lump, an area of thickening, or a dimple in the breast, and very less common signs include breast swelling and redness. A lump that is painless, hard and has uneven edges is more likely to be cancer. The classic symptom for breast cancer is a lump found in the breast or armpit. An aggressive type of this disease, inflammatory breast cancer, grows in sheets or nest of tumor cells that invade the skin and can resemble a rash. And other symptoms of breast cancer such as pain in the nipples, nipples may appear turning inward, thickening, scaliness or redness of the nipples or breast skin and irritation.

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Breast cancer type

Breast cancer type is categorized by whether it begins in the ducts or lobules, the organs responsible for breast milk production. Medullary carcinoma accounts for 15% of all breast cancer types. This breast cancer type represents 5% of all diagnosis. IPR015525 Breast cancer type 2 susceptibility protein Header EBIDatabasesInterPro Search Open in usermanual InterPro: ” /> Jump to: InterProScan Databases Documentation FTP site Help Click on the icon for context sensitive help from the user manual. The breast cancer type 2 susceptibility protein (BRCA2) is a breast tumour suppressor with a potential function in the cellular response to DNA damage. Some breast cancer types express one or more of these proteins on their cell surface, while others express none. Media Relations Contacts Online Press Kit Rumors, Myths, and Truths Glossary About the American Cancer Society Breastfeeding, Other Factors May Affect Risk of Breast Cancer TypeAtlanta 2008/08/25 -Factors such as age at menopause as well as a woman?s breastfeeding practices can influence her risk of developing certain types of breast cancer.

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Cancer accounts to a death of 6 million human lives per year. Modern medicine is aging with breath taking advances in cancer care with increasing awareness, preventing, detection, therapy, research and symptom management. Last 15 years has been a revolution. It is likely to fight Cancer out by getting an early detection especially at a pre cancer stage thus yielding best cure with much shorter treatment time, lesser cost, lesser body insult.

Breast cancer is the second most common kind of cancer in women and is characterized by the growth of malignant tumors in the glandular tissues of the breast. While no one knows why some women develop breast cancer and others do not, several variables have been identified as risk factors for breast cancer.

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Although the exact causes of breast cancer have yet to be identified, the risk increases gradually with age and for certain people there may be a family hereditary (genetic) component. Other risk factors may include a long menstrual cycle, early onset of menses, or late menopause; first pregnancy after age 31 ; a high-fat diet; endometrial or ovarian cancer; radiation exposure; estrogen therapy; antihypertensive therapy; alcohol and tobacco use; and preexisting fibrocystic disease. The recent discovery of the breast cancer gene BRCA 1 confirms the theory that the disease can be inherited from either the mother or the father. About half of all breast cancers develop in the upper outer quadrant. Growth rates vary. Theoretically, slow-growing breast cancer may take up to 8 years to become palpable at 3/8 “(1 cm). It spreads by way of the lymphatic system and the bloodstream through the right side of the heart to the lungs and to the other breast, chest wall, liver, bone, and brain. Signs and Symptoms Early detection and treatment are extremely important in curing breast cancer.”diagnosis: a preface to an autopsy”
“To confess ignorance is often wiser than to beat about the bush with a hypothetical diagnosis.”
“Being a reporter is as much a diagnosis as a job description” The warning signs and symptoms of breast cancer could include the following: Change in the size or shape of the breast Lump or thickening of tissue in the breast or armpit Dimpled or pulling of the skin over the breast Nipple discharge Retraction of the nipple Scaliness of the nipple Pain or Tenderness Abnormality on a mammogram Diagnostic tests Mammography, the essential test for breast cancer, can reveal a tumor that is too small to palpate. Fine-needle aspiration and excisional biopsy provide cells for histologic examination to confirm the diagnosis. Ultrasonography can distinguish between a fluid­filled cyst and a solid mass. Chest X-rays can pinpoint metastases in the chest. Scans of the bone, brain, liver, and other organs can detect distant metastases. Laboratory tests, such as alkaline phosphatase levels and liver function, can uncover distant metastases. Hormonal receptor assay can determine whether the tumor is estrogen or progesterone-dependent. This test guides decisions to use therapy that blocks the action of the estrogen hormone that supports tumor growth. Treatment The choice of treatment usually depends on the stage and type of disease, woman’s age and menopausal status, and disfiguring effects of surgery. Therapy may include any combination of surgery, radiation, chemotherapy, and hormone therapy. Surgery includes lumpectomy, partial mastectomy, simple or total mastectomy, modified radical mastectomy, and radical mastectomy. Lumpectomy. (say: lum- pek -tuh-mee), which removes the cancerous tumor from the breast. A woman usually has this surgery when the cancer is found early and when the lump is small and in only one part of the breast. Partial mastectomy (also known as segmental mastectomy or quadrantectomy) removes one-quarter or more of the breast. Simple or total mastectomy is the removal of the breast but not the lymph nodes or pectoral muscles. Modified radical mastectomy is the removal of the breast and some of the axillary lymph nodes. Radical mastectomy is the removal of the breast, pectoralis major and minor, and axillary lymph nodes. The use of this surgery has declined. Before or after tumor removal, primary radiation therapy may be effective for a patient who has a small tumor in early stages without distant metastases. Radiation therapy can also prevent or treat local recurrence. Preoperative breast irradiation also helps to sterilize the field, making the tumor more manageable surgically, especially in inflammatory breast cancer. Various cytotoxic drug combinations may be administered either as adjuvant therapy or as primary therapy. The patient may base her decision to undergo chemotherapy on several factors, including the cancer’s stage and hormonal receptor assay results. Chemotherapy commonly relies on a combination of drugs, such as cyclophosphamide, fluorouracil, methotrexate, doxorubicin, vincristine, paclitaxel, and prednisone. A typical regimen is cyclophosphamide, methotrexate, and fluorouracil; it’s used in premenopausal and postmenopausal women. Hormonal therapy lowers levels of estrogen and other hormones suspected of nourishing breast cancer cells. For example, antiestrogen therapy (specifically tamoxifen, which is most effective against tumors identified as estrogen receptor-positive) is used in postmenopausal women. Breast cancer patients may also receive estrogen, progesterone, androgen, or antiandrogen aminoglutethimide therapy. The success of these therapies provides growing evidence that breast cancer is systemic, not local, and has led to decline in ablation surgery. Prevention Doctors and scientists are working on finding cures for all types of breast cancer. They are researching new medicines that may even help prevent the disease. But in the meantime, it’s important for women to catch the disease early. Regular mammograms – together with monthly breast self-exams – are the best ways for women to protect themselves. You may want to ask the women you care about if they are taking these important steps.